

	  PROCHECK - Stereochemical Quality of Protein Structures
          -------------------------------------------------------
			and AQUA for PROCHECK-NMR
                        -------------------------

			CONFIDENTIALITY AGREEMENT
			-------------------------


In regard to the PROCHECK suite of programs, specified in Appendix 1
herewith and the AQUA suite of programs specified in Appendix 2 herewith
(the Software) supplied to us, the copyright and other intellectual
property rights to which belong to the authors, we

    __________________________________________________________________

undertake to the authors that we shall be bound by the following terms and
conditions:-

1. We will receive the Software and any related documentation in confidence
and will not use the same except for the purpose of the department's own 
research. The Software will be used only by such of our officers or
employees to whom it must reasonably be communicated to enable us to
undertake our research and who agree to be bound by the same confidence.
The department shall procure and enforce such agreement from its staff for
the benefit of the authors.

2. The publication of research using the Software must reference

   "Laskowski R A, MacArthur M W, Moss D S & Thornton J M (1993). PROCHECK:
   a program to check the stereochemical quality of protein
   structures. J. Appl.  Cryst., 26, 283-291."

and

   "Rullmann J A C (1996). AQUA, Computer Program, Department of NMR
   Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht
   University, The Netherlands."


3. Research shall take place solely at the department's premises at

    __________________________________________________________________

4. All forms of the Software will be kept in a reasonably secure place to
prevent unauthorised access.

5. Each copy of the Software or, if not practicable then, any package
associated therewith shall be suitably marked (and such marking maintained) 
with the following copyright notice: " Copyright 1992 M W MacArthur, R A
Laskowski, D S Moss, J A C Rullmann & J M Thornton All Rights Reserved".

6. The Software may be modified but any changes made shall be made
available to the authors.

7. The Software shall be used exclusively for academic teaching and
research. The Software will not be used for any commercial research or
research associated with an industrial company.

8. The confidentiality obligation in paragraph one shall not apply:

   (i)  to information and data known to the department at the time of
	receipt hereunder (as evidenced by its written records);

  (ii)	to information and data which was at the time of receipt in the 
	public domain or thereafter becomes so through no wrongful act of
	the department;

 (iii)	to information and data which the department receives from a third
	party not in breach of any obligation of confidentiality owed to
	the authors.


Please sign this Undertaking and return a copy of it to indicate that you 
have read, understood and accepted the above terms.


		      For and on behalf of _____________________________

		      _________________________________________________
		     
		      ..................................................

		      Dated ............................................


APPENDIX 1 - DETAILS OF THE PROCHECK SUITE OF PROGRAMS PROVIDED (v.3.4.3)
---------------------------------------------------------------

Files to be included
--------------------

         1. anglen.f            }
         2. anglen.inc          }
         3. bplot.f             }
         4. bplot.inc           }
         5. brkcln.par          }
         6. clean.f             }
         7. gfac2pdb.f          }
         8. gfac2pdb.inc        }
         9. mplot.f             }
        10. mplot.inc           } Source program files
        11. nb.c                }
        12. pplot.f             }
        13. pplot.inc           }
        14. ps.f                }
        15. rmsdev.f            }
        16. rmsdev.inc          }
        17. secstr.f            }
        18. sstruc.par          }
        19. tplot.f             }
        20. tplot.inc           }
        21. viol2pdb.f          }
        22. viol2pdb.inc        }
        23. vplot.f             }
        24. vplot.inc           }
        25. gfac2pdb.scr        }
        26. procheck.com      }
        27. procheck.scr      }
        28. procheck_comp.com }
        29. procheck_comp.scr }
        30. procheck_nmr.scr  }
        31. proplot.com       }
        32. proplot.scr       } Script files
        33. proplot_comp.scr  }
        34. proplot_nmr.scr   }
        35. proplot_comp.com  }
        36. prosub.com        }
        37. setup.com         }
        38. setup.scr         }
        39. viol2pdb.scr      }
        40. convax.for         }
        41. procomp.com        } Installation files
        42. procomp.scr        }
        43. maninst.ps       }
        44. manual.tar.Z     } Documentation files
        45. nmr_manual.tar.Z }
        46. procheck.dat       }
        47. procheck.prm       } Data
        48. procheck_comp.prm  } files
        49. procheck_nmr.prm   }


APPENDIX 2 - DETAILS OF THE AQUA SUITE OF PROGRAMS PROVIDED (v.0.40)
-----------------------------------------------------------

Files to be included
--------------------

Source files:-
------------

AquaCalc.c            AquaCalc.h
                      AquaData.h
AquaDist.c            AquaDist.h    
AquaFiles.c           AquaFiles.h     
AquaFuncts.c          AquaFuncts.h      
AquaFuncts_biosym.c   AquaFuncts_biosym.h             
AquaFuncts_cv.c       AquaFuncts_cv.h         
AquaFuncts_io.c       AquaFuncts_io.h         
AquaFuncts_pdb.c      AquaFuncts_pdb.h          
AquaFuncts_pdbmr.c    AquaFuncts_pdbmr.h            
AquaHow.c             AquaHow.h
                      AquaMacros.h   
AquaPseudo.c          AquaPseudo.h      
AquaStrucset.c        AquaStrucset.h
                      AquaTypes.h        
AquaWhat.c            AquaWhat.h    
Qext.c                Qext.h
Range.c               Range.h
                      cv_subs.h 

Script files:-
------------
ReadNrv.pm*           convDIANAtorsrestr    qdbext*
aqdrst*               convDISGEOdistrestr   qguessc*
aqpc*                 convDISGEOtorsrestr   qguessr*
aqpcsel               convMRTABLE           qhelp*
aquanal.pl*           convXPLORdistrestr    qmodr*
clean0*               convXPLORtorsrestr    qsplitr*
convBIOSYMdistrestr   makecmm*              qsumm*
convBIOSYMtorsrestr   qconvert*             qsumm_aux1*
convDIANAdistrestr    qconvr*               qsumm_aux2*

Documentation:-
-------------
README                 models.txt             qconvr.txt
aqpc.txt               mr.txt                 qdbext.txt
aqua_setup.txt         names.txt              qext.txt
biosym.txt             overview.txt           qhelp.txt
chains.txt             perl.txt               qsumm.txt
conversion.txt         procheck.txt           restraint_format.txt
dbas.txt               qanal.txt              setup.txt
intro.txt              qclean.txt             torsion.txt
log.txt                qconvert.txt           xplor.txt

Extras:-
------
joinpdb*               splitpdb*


Please complete the above form, sign it, and then send or fax to:-


Roman Laskowski
European Bioinformatics Institute,
Wellcome Trust Genome Campus,
Hinxton,
Cambridge, CB10 1SD,
United Kingdom
 
Fax:- +44 (0)1223 494 468

If you have any problems either installing the software or running it,
please e-mail your problems to:-

    roman@ebi.ac.uk

Questions about AQUA should be directed to Ton Rullmann at

      rull@nmr.chem.ruu.nl